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| c. 20 |
| | | Saul of Tarsus, later known as St Paul, has a Greek-speaking Jewish father who is a Roman citizen | |
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| c. 80 |
| | | The earliest of the Christian gospels, that of St Mark, is written down - possibly in Asia Minor or Syria | |
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| 158 |
| | | A new doctor, Galen, is appointed to look after the gladiators at Pergamum | |
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| 325 |
| | | Constantine convenes a council of 200 bishops at Nicaea to discuss the beliefs of Arius, which are deemed to be heresy | |
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| 330 |
| | | Constantine's new Christian city on the site of Byzantium is inaugurated, as Constantinople | |
|  | Constantinople, city walls
Fotofile CG
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| 337 |
| | | Constantine is at last baptized a Christian in Nicomedia, just a few days before his death | |
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| 360 |
| | | The first church of Santa Sophia in Constantinople, begun by Constantine himself, is completed | |
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| 361 |
| | | Julian, the new emperor in Constantinople, plans to reinstate the pagan cult of the ancient Roman empire | |
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| 363 |
| | | An apocryphal story states that Julian the Apostate, dying at Tarsus, acknowledges the victory of the Galilean, Jesus Christ | |
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| 378 |
| | | The Visigoths inflict a devastating defeat on a Roman army at Adrianople, and win for themselves the status of Roman federates | |
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